Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949982 | 0.80 | KCNA5 (0.46) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL3922461 | 0.77 | SLC6A2 (0.39) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1856673 | 0.73 | SLC6A2 (0.45) | CYP1A2ALDH1A1SLC6A2SLC6A4KDM4E | |
| SCHEMBL27792007 | 0.73 | SMN1; SMN2 (0.49) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL4980374 | 0.72 | SLC6A3 (0.48) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL25447692 | 0.72 | TSHR (0.47) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL21751670 | 0.72 | SLC6A2 (0.44) | CYP1A2ALDH1A1SLC6A2SLC6A4KDM4E | |
| SCHEMBL22420973 | 0.72 | SLC6A2 (0.44) | GAASMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL22559174 | 0.72 | SLC6A2 (0.44) | CYP1A2ALDH1A1SLC6A2SLC6A4KDM4E | |
| SCHEMBL20099923 | 0.72 | TSHR (0.47) | GAASMN1; SMN2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211744-B1 | PEPTIDIC AMINO-ALCOHOL DERIVATIVES CONTAINING A TETRA-SUBSTITUTED CARBON ATOM, INHIBITORS OF RENIN AND OF ACID PROTEASES, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS | SANOFI (FR) | 1991-12-04 | — | — | EP | claimed |