Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16070776 | 0.80 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL19741641 | 0.80 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10672122 | 0.80 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL11038239 | 0.76 | CHRM2 (0.51) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL28966996 | 0.76 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL4523411 | 0.74 | CYP2D6 (0.50) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3285780 | 0.74 | CYP2D6 (0.50) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL2132365 | 0.74 | CYP2D6 (0.50) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9818808 | 0.74 | CYP2D6 (0.53) | CHRM2CHRM1ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL9818778 | 0.74 | CYP2D6 (0.42) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259227-B1 | BENZHYDRYLOXYETHYL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme: LES LABORATOIRES MERAM (FR) | 1991-12-27 | — | — | EP | claimed |
| EP-0259227-A1 | Benzhydryloxyethyl piperidine derivatives, process for their preparation and pharmaceutical compositions containing them | Société anonyme: LES LABORATOIRES MERAM (FR) | 1988-03-09 | — | — | EP | claimed |