Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818971 | 1.00 | FFAR1 (0.46) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL9818868 | 0.89 | AKR1B1 (0.48) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL9818861 | 0.89 | AKR1B1 (0.48) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL9818765 | 0.81 | AKR1B1 (0.45) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL9818767 | 0.81 | AKR1B1 (0.45) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL15299338 | 0.78 | FFAR1 (0.69) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL15292428 | 0.78 | FFAR1 (0.69) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL14567198 | 0.76 | PPARD (0.53) | FFAR1PPARDPPARGPPARA | |
| SCHEMBL9818743 | 0.75 | BRD4 (0.39) | FFAR1PPARDPPARGAKR1B1ALDH1A1 | |
| SCHEMBL9818788 | 0.75 | AKR1B1 (0.40) | FFAR1PPARDPPARGAKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |