Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616286 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL12410714 | 0.77 | ALDH1A1 (0.41) | RET | |
| SCHEMBL31086695 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL12410717 | 0.74 | KMT2A (0.32) | RET | |
| SCHEMBL9344423 | 0.66 | — | — | |
| SCHEMBL12556553 | 0.65 | — | — | |
| SCHEMBL9818818 | 0.62 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL2930313 | 0.62 | ALDH1A1 (0.31) | RET | |
| SCHEMBL25458163 | 0.62 | KDM4E (0.33) | — | |
| SCHEMBL18235330 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213718-B1 | 1-DIMETHYLCARBAMOYL-3-SUBSTITUTED-5-SUBSTITUTED-1H-1,2,4-TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |