Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19215260 | 0.88 | ELANE (0.50) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL10397951 | 0.84 | ELANE (0.50) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL6562700 | 0.82 | POLB (0.50) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL17791332 | 0.79 | ELANE (0.57) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL2703931 | 0.79 | ELANE (0.57) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL56436 | 0.78 | ELANE (0.69) | ELANEKMT2AATMPOLBAPEX1 | |
| SCHEMBL14329773 | 0.78 | KMT2A (0.47) | ELANEKMT2AATMTHRBACACB | |
| SCHEMBL15814270 | 0.77 | ELANE (0.56) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL4594651 | 0.77 | ELANE (0.56) | ELANEKMT2AATMTHRBPOLB | |
| SCHEMBL4353041 | 0.77 | ELANE (0.56) | ELANEKMT2AATMTHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217205-B1 | COPOLYMERISABLE PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| EP-0217205-A2 | Copolymerisable photoinitiators | CIBA-GEIGY AG (CH) | 1987-04-08 | — | — | EP | disclosed |