SCHEMBL6562700

SCHEMBL6562700

C=C(C)C(=O)OCCOc1ccc(CC(C)(O)C(=O)C(C)(O)Cc2ccc(OCCOC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ACACB O00763 2/20 0.40
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
PPARG P37231 4/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819180 0.85 POLB (0.48) POLBAPEX1HTTTDP1ACACB
SCHEMBL454606 0.83 POLB (0.67) POLBAPEX1HTTTDP1THRB
SCHEMBL9818995 0.82 ELANE (0.48) POLBAPEX1HTTTDP1ACACB
SCHEMBL17036777 0.82 POLB (0.58) POLBAPEX1HTTTDP1ACACB
SCHEMBL331665 0.82 POLB (0.58) POLBAPEX1HTTTDP1THRB
SCHEMBL196997 0.82 THRB (0.57) ACACBTHRBALDH1A1LMNAPPARG
SCHEMBL25402465 0.80 POLB (0.61) POLBAPEX1HTTTDP1THRB
SCHEMBL9256662 0.80 ACACB (0.37) POLBAPEX1HTTTDP1ACACB
SCHEMBL59813 0.79 POLB (0.56) POLBAPEX1HTTTDP1THRB
SCHEMBL2831138 0.79 POLB (0.56) POLBAPEX1HTTTDP1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882749-B1 Urethane prepolymer, process for producing the same and pressure-sensitive adhesive comprising the same KYOEISHA CHEMICAL CO LTD (JP) 2004-03-24 EP claimed
US-6022907-A POLYESTERURETHANE FROM DIMER ACIDS, REACTIVE END GROUPSA KYOEISHA CHEMICAL CO., LTD. (JP) 2000-02-08 US claimed
EP-0882749-A2 Urethane prepolymer, process for producing the same and pressure-sensitive adhesive comprising the same KYOEISHA CHEMICAL CO., LTD. (JP) 1998-12-09 EP claimed
US-10981352-B2 Method for producing optical member, and optical member SHARP KABUSHIKI KAISHA (JP) 2021-04-20 US disclosed
CN-109073786-B Method for manufacturing optical member and optical member 夏普株式会社 2020-10-16 CN disclosed
US-20190118504-A1 METHOD FOR PRODUCING OPTICAL MEMBER, AND OPTICAL MEMBER SHARP KABUSHIKI KAISHA (JP) 2019-04-25 US disclosed
CN-109073786-A The manufacturing method and optical component of optical component 夏普株式会社 2018-12-21 CN disclosed