SCHEMBL9819280

SCHEMBL9819280

C=C(C)C(=O)OC(CC)[Si](O)(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3744246 0.85 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL2009455 0.85 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL7864106 0.83 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL8074770 0.81 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL1677860 0.81 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL9154189 0.80 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL4393502 0.79 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL524563 0.79 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL15477683 0.79 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL15477758 0.79 TSHR (0.38) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0228209-B1 ORAL HYGIENE PRODUCT UNILEVER PLC (GB) 1991-10-30 EP disclosed
US-4837007-A TIME-RELEASING FLUORIDE IONS BY MIXING TWO SUBSTANCES LEVER BROTHERS COMPANY (US) 1989-06-06 US disclosed
EP-0228209-A2 Oral hygiene product UNILEVER PLC (GB) 1987-07-08 EP disclosed