SCHEMBL524563

SCHEMBL524563

C=C(C)C(=O)OC(CC)[Si](Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.37
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477797 0.92 ALDH1A1 (0.35) TSHRALDH1A1THRB
SCHEMBL933010 0.87 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL1719176 0.87 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL15477761 0.85 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL9154189 0.85 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL28901403 0.85 THRB (0.31) TSHRTHRB
SCHEMBL10885738 0.84 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL2009455 0.82 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL1677860 0.82 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL15477477 0.81 TSHR (0.45) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059985-A Methacryloxypropyl triacetyl preparation method of oxo silane 山东硅科新材料有限公司 2026-05-19 CN claimed
US-20260118766-A1 Silicon containing coating compositions and uses thereof PIBOND OY (FI) 2026-04-30 US claimed
CN-121571356-A Environment-friendly emission-reducing type vehicle tail gas exhaust pipe and preparation process thereof 扬州翰昇汽车配件有限公司 2026-02-27 CN claimed
EP-4673493-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF Pibond Oy (FI) 2026-01-07 EP claimed
WO-2024180279-A1 SILICON CONTAINING COATING COMPOSITIONS AND USES THEREOF PIBOND OY (FI) 2024-09-06 WO claimed
EP-4329933-A1 HYDROLYTICALLY STABLE ZWITTERIONIC CHROMATOGRAPHIC MATERIALS Waters Technologies Corporation (US) 2024-03-06 EP claimed
CN-117222480-A Hydrolysis-stable zwitterionic chromatographic material 沃特世科技公司 2023-12-12 CN claimed
CN-114478960-B Plugging material and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-114349513-B Insulating radiating fin preparation process and insulating radiating fin 东莞市鸿亿导热材料有限公司 2023-03-17 CN claimed
CN-115353814-A Heat-insulating and sound-insulating glass laminating adhesive and preparation method thereof 浙江祥邦科技股份有限公司 2022-11-18 CN claimed
US-6399037-B1 LOW VISCOSITY NONSETTLING SURFACE METHACRYLOXYPROPYL HALOSILANE SILANIZED; STABLE SOL; ABRASIVE RESISTANT; INCREASED COMPRESSION AND BONDING STRENGTH; VARNISHES, SEALANTS, AND BONDING AGENTS DENTSPLY DETREY GMBH (DE) 2002-06-04 US claimed
US-20020065337-A1 Dental materials having a nanoscale filler DENTSPLY DETREY GMBH. 2002-05-30 US claimed
EP-1024778-A1 PROTECTIVE VARNISH FOR DENTIN DENTSPLY INTERNATIONAL, INC. (US) 2000-08-09 EP claimed
EP-0969789-A2 DENTAL MATERIALS HAVING A NANOSCALE FILLER DENTSPLY INTERNATIONAL, INC. (US) 2000-01-12 EP claimed
WO-1999020227-A1 PROTECTIVE VARNISH FOR DENTIN DENTSPLY INTERNATIONAL INC. (US) 1999-04-29 WO claimed
WO-1999017716-A2 DENTAL MATERIALS HAVING A NANOSCALE FILLER DENTSPLY INTERNATIONAL INC. (US) 1999-04-15 WO claimed
EP-0495936-A4 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER 1993-03-17 EP claimed
EP-0495936-A1 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1992-07-29 EP claimed
WO-1991019606-A1 METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER ADVANCED GLASS TREATMENT SYSTEMS (US) 1991-12-26 WO claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118766-A1 Silicon containing coating compositions and uses thereof ITGA8, SMCHD1, GCN1 TSHR 957/4885ALDH1A1 1290/4885THRB 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.