Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 10/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408348 | 0.83 | FDPS (0.35) | FDPSALDH1A1 | |
| SCHEMBL31595181 | 0.79 | — | — | |
| SCHEMBL9045147 | 0.78 | TSHR (0.37) | TSHRFDPSGGPS1ALDH1A1 | |
| SCHEMBL20656782 | 0.78 | FDPS (0.36) | TSHRFDPSGGPS1ESR1ESR2 | |
| SCHEMBL6052827 | 0.77 | — | — | |
| SCHEMBL5697306 | 0.77 | — | — | |
| SCHEMBL233642 | 0.74 | FDPS (0.33) | TSHRFDPSGGPS1ESR1ESR2 | |
| SCHEMBL11087075 | 0.72 | TSHR (0.41) | TSHRFDPSALDH1A1LMNA | |
| SCHEMBL11857578 | 0.72 | TSHR (0.41) | TSHRFDPSALDH1A1LMNA | |
| SCHEMBL7616020 | 0.72 | TSHR (0.41) | TSHRFDPSALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444152-A1 | CERTAIN 2-(2',3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES. | ICI AMERICA INC (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0369803-A1 | Trisubstituted benzoic acid intermediates | ZENECA INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0316491-A1 | Herbicidal 2-pyridyl and 2-pyrimidine carbonyl 1,3-cyclohexanediones | STAUFFER AGRICULTURAL CHEMICALS COMPANY, INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317158-A2 | Certain 2-benzoyl-5-hydroxy-4,4,6,6-tetra-substituted-1,3-cyclohexanediones | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0268795-A2 | 2-(2-substituted benzoyl)-4-(substituted oxy or substituted thio)-1,3-cyclohexanediones, a process for their production and a herbicidal composition containing them | STAUFFER CHEMICAL COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0264859-A2 | 2-(2-substituted benzoyl)-4-(substituted)-1,3-cyclohexanediones, a process for their production and a herbicidal composition containing them | STAUFFER CHEMICAL COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |
| EP-0264737-A2 | 2-(2-substituted benzoyl)-4-(substituted imino, oximino or carbonyl)-1,3-cyclo-hexanediones, a process for their production, and a herbicidal composition containing them | STAUFFER CHEMICAL COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |
| EP-0255584-A2 | Certain substituted 4-bezoyl-3,5-dioxotetrahydropyrans and thiopyrans | STAUFFER CHEMICAL COMPANY (US) | 1988-02-10 | — | — | EP | disclosed |
| EP-0253124-A2 | Certain substituted 3-(substituted oxy)-2-benzoyl-cyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249813-A1 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |
| EP-0249151-A2 | Certain 2-phenylacetyl-1,3,5-cyclohexanetriones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0249150-A1 | Certain 3-(substituted thio)-2-benzoyl-cyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0249149-A1 | Certain 3-benzoyl-4-oxolactams | STAUFFER CHEMICAL COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| US-4246189-A | FOR EASE OF MATERIALS HANDLING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-01-20 | — | — | US | disclosed |