Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.41 |
| ▸ | NPY1R | P25929 | 6/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819630 | 1.00 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RPDCD1LG2 | |
| SCHEMBL30903440 | 0.93 | BACE1 (0.43) | NPY4RNPY1RNPY2RNPY5RCTSD | |
| SCHEMBL22687904 | 0.92 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| SCHEMBL29985236 | 0.91 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RKISS1R | |
| SCHEMBL29784994 | 0.91 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RPDCD1LG2 | |
| SCHEMBL30615287 | 0.91 | VIPR2 (0.42) | NPY4RNPY1RNPY2RNPY5RCTSD | |
| SCHEMBL29789057 | 0.90 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| SCHEMBL30117177 | 0.90 | PDCD1LG2 (0.42) | NPY4RNPY1RNPY2RNPY5RPDCD1LG2 | |
| SCHEMBL9852051 | 0.89 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| SCHEMBL29697038 | 0.89 | NPY4R (0.42) | NPY4RNPY1RNPY2RNPY5RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364561-A4 | FACTOR VII/VIIA ACTIVE SITE INHIBITORS | — | 1991-06-19 | — | — | EP | disclosed |
| US-5023236-A | Tripeptides having an arginine at the C-terminus and a hydroxy-containing amino acid in the second position; anticoagulants; antiinflammatory agents; reversible | CORVAS, INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0364561-A1 | FACTOR VII/VIIa ACTIVE SITE INHIBITORS | CORVAS, INC. (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989009612-A1 | FACTOR VII/VIIa ACTIVE SITE INHIBITORS | CORVAS, INC. (US) | 1989-10-19 | — | — | WO | disclosed |