SCHEMBL29985236

SCHEMBL29985236

CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.47
NPY1R P25929 9/20 0.47
NPY5R Q15761 8/20 0.47
NPY2R P49146 5/20 0.47
KISS1R Q969F8 3/20 0.38
NOD1 Q9Y239 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621731 0.97 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31415957 0.93 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16432550 0.92 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16432553 0.92 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2R
SCHEMBL7159410 0.92 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL27712094 0.92 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL7098633 0.92 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL29492567 0.92 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL29492562 0.92 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RNOD1
SCHEMBL31696331 0.91 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540349-B2 Horseshoe crab factor B variant SEIKAGAKU CORPORATION (JP) 2026-02-03 US disclosed
US-20260014211-A1 METHODS AND COMPOSITIONS FOR INCREASING BACTERIAL ENGRAFTMENT AND POPULATIONS IN THE GUT MICROBIOME UNIV CHICAGO (US) 2026-01-15 US disclosed
EP-4488372-A2 METHOD FOR ENHANCING SENSITIVITY OF ENDOTOXIN MEASURING AGENT Seikagaku Corporation (JP) 2025-01-08 EP disclosed
WO-2024020466-A1 METHODS AND COMPOSITIONS FOR INCREASING BACTERIAL ENGRAFTMENT AND POPULATIONS IN THE GUT MICROBIOME THE UNIVERSITY OF CHICAGO (US) 2024-01-25 WO disclosed
CN-110366592-B Limulus factor B modification 生化学工业株式会社 2024-01-23 CN disclosed
EP-3591049-B1 HORSESHOE CRAB FACTOR B VARIANT SEIKAGAKU KOGYO CO LTD (JP) 2023-11-22 EP disclosed
US-20230193349-A1 HORSESHOE CRAB FACTOR B VARIANT SEIKAGAKU CORPORATION (JP) 2023-06-22 US disclosed
CN-115697069-A Hypoallergenic recombinant milk proteins and compositions comprising the same 完美日股份有限公司 2023-02-03 CN disclosed
US-11499177-B2 Horseshoe crab factor B variant SEIKAGAKU CORPORATION (JP) 2022-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540349-B2 Horseshoe crab factor B variant RNGTT, UPF1, F13B NPY4R 2383/4885NPY1R 2519/4885NPY5R 3716/4885
US-20260014211-A1 METHODS AND COMPOSITIONS FOR INCREASING BACTERIAL ENGRAFTMENT AND POPULATIONS IN THE GUT MICROBIOME FABP2, CD74, SLC10A2 NPY4R 2863/4885NPY1R 2422/4885NPY5R 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.