Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSH | P09668 | 4/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020386 | 1.00 | CTSK (0.40) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL8020431 | 0.97 | — | — | |
| SCHEMBL8022369 | 0.92 | — | — | |
| SCHEMBL8010067 | 0.86 | — | — | |
| SCHEMBL5906000 | 0.79 | CYP1A2 (0.37) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL7739849 | 0.78 | CYP1A2 (0.40) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL3155857 | 0.78 | CYP1A2 (0.40) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL7491521 | 0.78 | CYP1A2 (0.40) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL1192695 | 0.78 | CYP1A2 (0.40) | CTSKCTSLCTSBCYP1A2CTSH | |
| SCHEMBL198845 | 0.78 | CYP1A2 (0.40) | CTSKCTSLCTSBCYP1A2CTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |