Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290039 | 0.78 | MEN1 (0.38) | MEN1KMT2ACYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL5918689 | 0.75 | MEN1 (0.35) | MEN1KMT2ACYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL395756 | 0.73 | MEN1 (0.40) | MEN1KMT2ANQO2CYP2A6ALOX12 | |
| SCHEMBL30390125 | 0.71 | MEN1 (0.39) | MEN1KMT2ANQO2CA1CA2 | |
| Indene SCHEMBL1162574 | 0.70 | — | — | |
| SCHEMBL5475167 | 0.70 | MEN1 (0.38) | MEN1KMT2AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL14062348 | 0.68 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL308186 | 0.67 | MEN1 (0.48) | MEN1KMT2ANQO2CYP2A6ALOX12 | |
| SCHEMBL30003181 | 0.67 | MEN1 (0.48) | MEN1KMT2ANQO2CYP2A6ALOX12 | |
| SCHEMBL7914941 | 0.66 | MEN1 (0.52) | MEN1KMT2ANQO2CYP2A6ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |