SCHEMBL7914941

SCHEMBL7914941

c1ccc2cc3c(cc2c1)Cc1cc2ccccc2cc1C3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP3A4 P08684 3/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 3/20 0.45
TP53 P04637 2/20 0.45
MAPK1 P28482 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
PKM P14618 1/20 0.45
CYP2C19 P33261 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP2A6 P11509 5/20 0.44
ALOX12 P18054 1/20 0.44
NQO2 P16083 1/20 0.41
CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274423 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL29604701 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL1808685 1.00 MEN1 (0.52) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL8662572 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL30376019 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL19810032 0.94 MEN1 (0.48) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL14800367 0.89 MEN1 (0.44) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL30924248 0.85 MEN1 (0.46) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL1655232 0.85 MEN1 (0.46) MEN1KMT2ACYP3A4TSHRHSD17B10
SCHEMBL4621881 0.84 MEN1 (0.41) MEN1KMT2ACYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113860984-A Magnesium-activated ligand-promoted chromium-catalyzed polycyclic aromatic hydrocarbon and olefin regioselective hydrogenation method 延安大学 2021-12-31 CN disclosed
US-10604469-B2 Method for the preparation of a partially hydrogenated polyacene and an intermediate thereof FUNDACIO INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) 2020-03-31 US disclosed
CN-107216229-B A kind of method of chromic salts/methyl-magnesium-bromide selective catalytic hydrogenation polycyclic aromatic hydrocarbon 四川大学 2019-07-09 CN disclosed
US-20190161426-A1 METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF UNIVERSITAT ROVIRA I VIRGILI (ES) 2019-05-30 US disclosed
WO-2018019436-A1 METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) 2018-02-01 WO disclosed
EP-3275876-A1 METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF Fundació Institut Català D'investigació Quimica (ES) 2018-01-31 EP disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10604469-B2 Method for the preparation of a partially hydrogenated polyacene and an intermediate thereof PARN, PCBP1, PARG MEN1 973/4885KMT2A 528/4885CYP3A4 584/4885
US-20190161426-A1 METHOD FOR THE PREPARATION OF A PARTIALLY HYDROGENATED POLYACENE AND AN INTERMEDIATE THEREOF PARN, PCBP1, PARG MEN1 973/4885KMT2A 528/4885CYP3A4 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.