Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819753 | 0.82 | PTAFR (1.00) | PTAFRALDH1A1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL9819996 | 0.81 | PTAFR (0.98) | PTAFRALDH1A1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL9819839 | 0.79 | PTAFR (0.93) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL9744339 | 0.77 | PTAFR (0.91) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL10647450 | 0.72 | PTAFR (0.64) | PTAFRALDH1A1KDM4EALOX15SIGMAR1 | |
| SCHEMBL9202842 | 0.71 | PTAFR (0.78) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL4797847 | 0.70 | KDM4E (0.56) | PTAFRALDH1A1KDM4EALOX15SIGMAR1 | |
| SCHEMBL9199023 | 0.70 | PTAFR (0.77) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL9744337 | 0.70 | PTAFR (0.74) | PTAFRALDH1A1KDM4E | |
| SCHEMBL24581185 | 0.69 | HRH3 (0.71) | ALDH1A1SIGMAR1FAAHUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |