Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819818 | 0.81 | PTAFR (0.58) | PTAFRALDH1A1KDM4EALOX15SIGMAR1 | |
| SCHEMBL9819909 | 0.78 | PTAFR (0.42) | PTAFRALDH1A1KDM4E | |
| SCHEMBL9819753 | 0.78 | PTAFR (1.00) | PTAFRALDH1A1KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL9819996 | 0.77 | PTAFR (0.98) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL9740818 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL10425283 | 0.77 | ALDH1A1 (0.52) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9819839 | 0.75 | PTAFR (0.93) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL9744339 | 0.73 | PTAFR (0.91) | PTAFRALDH1A1KDM4EALOX15 | |
| SCHEMBL9819800 | 0.72 | PTAFR (0.69) | PTAFRALDH1A1KDM4EALOX15SIGMAR1 | |
| SCHEMBL9853914 | 0.71 | PTAFR (0.53) | PTAFRALDH1A1KDM4EALOX15FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |