Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213367 | 1.00 | SIGMAR1 (0.82) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL29107049 | 1.00 | SIGMAR1 (0.82) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL11132388 | 1.00 | SIGMAR1 (0.82) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL9034885 | 1.00 | SIGMAR1 (0.82) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL29266756 | 1.00 | SIGMAR1 (0.82) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL7553527 | 0.98 | SIGMAR1 (0.79) | SIGMAR1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL9819972 | 0.98 | SIGMAR1 (0.85) | SIGMAR1L3MBTL1 | |
| SCHEMBL3119923 | 0.96 | SIGMAR1 (0.82) | SIGMAR1 | |
| SCHEMBL9819833 | 0.96 | SIGMAR1 (0.82) | SIGMAR1 | |
| SCHEMBL8625670 | 0.96 | SIGMAR1 (0.81) | SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |