Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.60 |
| ▸ | MIF | P14174 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819728 | 1.00 | NAAA (0.60) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819891 | 1.00 | NAAA (0.60) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819844 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819738 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819842 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819828 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819781 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819790 | 0.95 | NAAA (0.64) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL9819893 | 0.93 | NAAA (0.62) | NAAAMIFSIGMAR1MAOAMAOB | |
| SCHEMBL8897206 | 0.93 | HTR3A (0.57) | NAAAMIFSIGMAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |