Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9819882 | 0.99 | PTAFR (0.73) | PTAFRKDM4EALDH1A1TBXAS1POLB | |
| Fumaric Acid SCHEMBL9819820 | 0.95 | PTAFR (0.70) | PTAFRKDM4EALDH1A1TBXAS1POLB | |
| Fumaric Acid SCHEMBL9819823 | 0.95 | PTAFR (0.70) | PTAFRKDM4EALDH1A1TBXAS1POLB | |
| SCHEMBL9744339 | 0.86 | PTAFR (0.91) | PTAFRKDM4EALDH1A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL9819839 | 0.86 | PTAFR (0.93) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9819753 | 0.85 | PTAFR (1.00) | PTAFRKDM4EALDH1A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL9819996 | 0.85 | PTAFR (0.98) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9819716 | 0.84 | PTAFR (0.53) | PTAFRKDM4EALDH1A1TBXAS1POLB | |
| SCHEMBL9819827 | 0.84 | PTAFR (0.77) | PTAFRKDM4EALDH1A1TBXAS1 | |
| SCHEMBL9744361 | 0.84 | PTAFR (0.71) | PTAFRKDM4EALDH1A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | claimed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | claimed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |