Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.46 |
| ▸ | CHAT | P28329 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819962 | 1.00 | RXRA (0.46) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL9819837 | 0.89 | RXRA (0.44) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL9819836 | 0.89 | RXRA (0.44) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL6002917 | 0.85 | RXRA (0.49) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL9819923 | 0.85 | RXRA (0.49) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL23460038 | 0.81 | CHAT (0.47) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL1469843 | 0.81 | TLR8 (0.50) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL9830930 | 0.81 | CHAT (0.56) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL1469842 | 0.81 | TLR8 (0.50) | RXRASMPD2CHATHDAC8HDAC6 | |
| SCHEMBL9830937 | 0.81 | CHAT (0.56) | RXRASMPD2CHATHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |