Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9819897 | 0.99 | TBXAS1 (0.56) | TBXAS1ALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL9645119 | 0.88 | TBXAS1 (0.57) | TBXAS1ALDH1A1KDM4E | |
| SCHEMBL9645902 | 0.88 | TBXAS1 (0.57) | TBXAS1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9646825 | 0.87 | TBXAS1 (0.57) | TBXAS1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9646010 | 0.87 | TBXAS1 (0.57) | TBXAS1ALDH1A1KDM4E | |
| SCHEMBL9819940 | 0.84 | KDM4E (0.56) | TBXAS1ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9646789 | 0.84 | TBXAS1 (0.57) | TBXAS1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9819825 | 0.83 | KDM4E (0.55) | TBXAS1ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9819798 | 0.83 | KDM4E (0.69) | TBXAS1ALDH1A1KDM4E | |
| SCHEMBL9646821 | 0.83 | TBXAS1 (0.56) | TBXAS1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |