SCHEMBL9820099

SCHEMBL9820099

Cc1ccc(S(=O)(=O)c2ccc(C)cc2Cc2ccccc2)c(Cc2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 1/20 0.43
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
BCL2 P10415 1/20 0.40
BCL2L1 Q07817 1/20 0.40
ALDH1A1 P00352 5/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 2/20 0.40
POLB P06746 1/20 0.40
ALOX12 P18054 1/20 0.40
GFER P55789 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
CA12 O43570 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9820124 0.89 CNR2 (0.39) MEN1KMT2ABCHEACHETDP1
SCHEMBL1700674 0.87 MEN1 (0.44) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL30988955 0.87 MEN1 (0.44) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL909723 0.87 MEN1 (0.46) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL6605222 0.84 MEN1 (0.45) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL9820025 0.79 MEN1 (0.57) MEN1KMT2ACYP3A4BCL2BCL2L1
SCHEMBL9820069 0.79 MEN1 (0.42) MEN1KMT2ACYP3A4BCHEACHE
SCHEMBL27653272 0.78 MEN1 (0.39) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL16759739 0.78 MEN1 (0.39) MEN1KMT2ACYP3A4CYP2D6TSHR
SCHEMBL9066731 0.78 BCL2 (0.50) CYP3A4CYP2D6TSHRCYP2C19BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182299-B1 A CURABLE FLUOROELASTOMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-04-03 EP disclosed
US-4748208-A FLUOROPOLYMER, BIS/PHOSPHINE/IMINIUM HALIDE, POLYHYDROXY CURING AGENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-05-31 US disclosed
EP-0182299-A2 A curable fluoroelastomer composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-05-28 EP disclosed