SCHEMBL9820124

SCHEMBL9820124

Cc1ccc(Cc2cc(C)ccc2S(=O)(=O)c2ccc(C)cc2Cc2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.39
GAA P10253 1/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
DAO P14920 1/20 0.38
BCHE P06276 3/20 0.37
ACHE P22303 3/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
SRD5A2 P31213 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RET P07949 1/20 0.35
MAPT P10636 1/20 0.35
KDR P35968 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9820099 0.89 MEN1 (0.45) CA9BCHEACHEMEN1KMT2A
SCHEMBL11286354 0.84 MEN1 (0.36) CNR2PDE3BPDE3ACA1CA2
SCHEMBL9820069 0.81 MEN1 (0.42) GAACA1CA2CA9BCHE
SCHEMBL4138945 0.80 RAPGEF4 (0.42) GAAKMT2AHTTTDP1L3MBTL1
SCHEMBL9820115 0.78 TAAR1 (0.36) GAAKMT2AHTTTDP1L3MBTL1
SCHEMBL14881082 0.77 ALDH1A1 (0.43) GAACA1CA2CA9ACHE
SCHEMBL5676946 0.77 MEN1 (0.43) CNR2BCHEACHEMEN1KMT2A
SCHEMBL8079008 0.77 KMT2A (0.40) GAACA1CA2CA9KMT2A
SCHEMBL11680272 0.77 MEP1B (0.38) GAAMEN1KMT2AHTTTDP1
Methylamine SCHEMBL28132703 0.77 RAPGEF4 (0.41) GAACA1CA2CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182299-B1 A CURABLE FLUOROELASTOMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-04-03 EP disclosed
US-4748208-A FLUOROPOLYMER, BIS/PHOSPHINE/IMINIUM HALIDE, POLYHYDROXY CURING AGENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-05-31 US disclosed
EP-0182299-A2 A curable fluoroelastomer composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-05-28 EP disclosed