Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6488253 | 0.79 | GRM6 (0.56) | GRM6ACES1PR1S1PR5AGTR2 | |
| SCHEMBL23464974 | 0.79 | GRM6 (0.56) | GRM6ACES1PR1S1PR5AGTR2 | |
| SCHEMBL2771075 | 0.76 | GRM6 (0.54) | GRM6S1PR1S1PR5AGTR2MEN1 | |
| SCHEMBL2771498 | 0.76 | GRM6 (0.54) | GRM6S1PR1S1PR5AGTR2MEN1 | |
| SCHEMBL2771071 | 0.76 | GRM6 (0.54) | GRM6S1PR1S1PR5AGTR2MEN1 | |
| SCHEMBL25245895 | 0.75 | GRM6 (0.47) | GRM6ACES1PR1S1PR5GRM2 | |
| SCHEMBL8126352 | 0.75 | GRM6 (0.47) | GRM6ACES1PR1S1PR5AGTR2 | |
| SCHEMBL25297483 | 0.75 | GRM6 (0.47) | GRM6ACES1PR1S1PR5GRM2 | |
| SCHEMBL8126349 | 0.75 | GRM6 (0.47) | GRM6ACES1PR1S1PR5AGTR2 | |
| Hydrochloric Acid SCHEMBL7450701 | 0.74 | GRM6 (0.46) | GRM6ACES1PR1S1PR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160451-B1 | DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTER DERIVATIVE ISOMERS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | claimed |