Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338252 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL9338251 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL9693162 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EL3MBTL1TDP1MAPT | |
| SCHEMBL9693160 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EL3MBTL1TDP1MAPT | |
| SCHEMBL9019998 | 0.84 | CA1 (0.52) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL7168869 | 0.84 | AKR1C3 (0.50) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL9019902 | 0.84 | CA1 (0.47) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL8653469 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL8958972 | 0.84 | AKR1C3 (0.50) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD | |
| SCHEMBL9335995 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EL3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |