Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578183 | 0.81 | CDK5 (0.43) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27984414 | 0.79 | MAPT (0.42) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10576372 | 0.78 | POLB (0.38) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10579304 | 0.77 | MAPT (0.39) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10580564 | 0.77 | RAB9A (0.43) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9820292 | 0.74 | MAPT (0.35) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8412603 | 0.74 | KMT2A (0.41) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10575831 | 0.74 | TDP1 (0.41) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10581261 | 0.73 | MAPT (0.34) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6672241 | 0.72 | MAPT (0.41) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | claimed |