Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 7/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7290196 | 0.99 | CPA3 (0.49) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL7434085 | 0.90 | CPA3 (0.41) | CPA3CYP1A2CPA1FOLH1SLC1A3 | |
| SCHEMBL7300947 | 0.87 | KMT2A (0.43) | CPA3CYP1A2FOLH1REN | |
| SCHEMBL7382334 | 0.87 | CYP1A2 (0.47) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL7301076 | 0.87 | CYP1A2 (0.47) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL7273137 | 0.82 | CYP1A2 (0.54) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL7273127 | 0.82 | CYP1A2 (0.54) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL9445001 | 0.81 | CYP1A2 (0.53) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL9445007 | 0.81 | CYP1A2 (0.53) | CPA3CYP1A2CPA1FOLH1CPB1 | |
| SCHEMBL7414519 | 0.81 | CYP1A2 (0.53) | CPA3CYP1A2CPA1FOLH1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063208-A | Cardiovascular disorders, vision defects | ABBOTT LABORATORIES (US) | 1991-11-05 | — | — | US | disclosed |
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |