Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820286 | 0.79 | ALDH1A1 (0.49) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL10579453 | 0.78 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL9771617 | 0.78 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL9820246 | 0.74 | KMT2A (0.48) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL4619073 | 0.74 | KAT2B (0.51) | MAPTALDH1A1TSHRTDP1GAA | |
| SCHEMBL9820239 | 0.73 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL10577037 | 0.72 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL9820296 | 0.72 | TSHR (0.47) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| SCHEMBL11022280 | 0.72 | KMT2A (0.59) | MAPTALDH1A1SMN1; SMN2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL5063788 | 0.72 | KAT2B (0.54) | MAPTALDH1A1TSHRTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | claimed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | claimed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | claimed |
| EP-0303826-B1 | SUBSTITUTED 2-NITRO METAPHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING KERATINOUS FIBRES AND ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1991-02-27 | — | — | EP | disclosed |
| US-4863482-A | FROM A TRIHALONITROBENZENE | L'OREAL (FR) | 1989-09-05 | — | — | US | disclosed |
| EP-0303826-A1 | Substituted 2-nitro metaphenylene diamines, process for their preparation and their use in dyeing keratinous fibres and especially human hair | L'OREAL (FR) | 1989-02-22 | — | — | EP | disclosed |