Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10756921 | 0.99 | KMT2A (0.55) | KMT2AGSK3BPIM1GSK3APIM3 | |
| SCHEMBL31318272 | 0.87 | GSK3B (0.54) | KMT2AGSK3BPIM1GSK3APIM3 | |
| SCHEMBL10702920 | 0.80 | PIM3 (0.42) | KMT2AGSK3BPIM1GSK3APIM3 | |
| SCHEMBL8983630 | 0.76 | KMT2A (0.36) | KMT2A | |
| Hydrochloric Acid SCHEMBL9044154 | 0.72 | KMT2A (0.33) | KMT2AGSK3BEPHA2FLT4RARB | |
| Tosufloxacin SCHEMBL34354 | 0.72 | KMT2A (1.00) | KMT2AGSK3BEPHA2FLT4RARB | |
| Tosufloxacin SCHEMBL29383684 | 0.72 | KMT2A (1.00) | KMT2AGSK3BEPHA2FLT4RARB | |
| Tosufloxacin SCHEMBL34355 | 0.72 | KMT2A (1.00) | KMT2AGSK3BEPHA2FLT4RARB | |
| Tosufloxacin SCHEMBL9323984 | 0.72 | KMT2A (1.00) | KMT2AGSK3BEPHA2FLT4RARB | |
| SCHEMBL8390726 | 0.71 | GLA (0.34) | KMT2AGSK3BEPHA2FLT4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057523-A | Water soluble bactericide | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| US-4956475-A | REDUCTIVE ACETYLATION OF THE 3-AZIDO DERIVATIVE USING THIOACETIC ACID TO OBTAIN THE CORRESPONDING ACETAMIDE | ABBOTT LABORATORIES (US) | 1990-09-11 | — | — | US | disclosed |