Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846686 | 0.77 | — | — | |
| SCHEMBL20511739 | 0.69 | GAA (0.42) | GSTP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1804084 | 0.68 | — | — | |
| SCHEMBL20511807 | 0.68 | TP53 (0.37) | GSTP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20511846 | 0.68 | HIF1A (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6575838 | 0.67 | HDAC4 (0.41) | GSTP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20434138 | 0.66 | POLB (0.41) | MAPTALDH1A1 | |
| SCHEMBL745837 | 0.64 | — | — | |
| SCHEMBL15800663 | 0.64 | — | — | |
| SCHEMBL11502520 | 0.63 | MAPT (0.41) | GSTP1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249813-B1 | CERTAIN SUBSTITUTED 3-AMINO-2-BENZOYLCYCLOHEX-2-ENONES | STAUFFER CHEMICAL COMPANY (US) | 1991-07-24 | — | — | EP | disclosed |
| US-4775411-A | HERBICIDES | STAUFFER CHEMICA COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0249813-A1 | Certain substituted 3-amino-2-benzoylcyclohex-2-enones | STAUFFER CHEMICAL COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |