Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569125 | 0.88 | PTPN1 (0.41) | TSHRL3MBTL1CHRM3ALDH1A1MAPT | |
| SCHEMBL819613 | 0.81 | CHRM3 (0.42) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL5799259 | 0.80 | GSTP1 (0.44) | GSTP1TSHRL3MBTL1ALDH1A1MAPT | |
| SCHEMBL15957919 | 0.80 | PTPN1 (0.52) | TSHRL3MBTL1CHRM3ALDH1A1MAPT | |
| SCHEMBL10933450 | 0.78 | GSTP1 (0.40) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL10937960 | 0.77 | CHRM3 (0.45) | TSHRL3MBTL1CHRM3ALDH1A1MAPT | |
| SCHEMBL747380 | 0.75 | HIF1A (0.38) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL11883308 | 0.74 | HIF1A (0.37) | HDAC4HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL44118 | 0.74 | — | — | |
| SCHEMBL3369781 | 0.72 | MAPT (0.37) | HDAC4HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002058-A9 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX INC (US) | 2004-07-08 | — | — | WO | disclosed |
| EP-1404344-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | Anabonix, Inc. (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20030119800-A1 | Bone anabolic compounds and methods of use | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-06-26 | — | — | US | disclosed |
| WO-2003002058-A2 | BONE ANABOLIC COMPOUNDS AND METHODS OF USE | ANABONIX, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119800-A1 | Bone anabolic compounds and methods of use | SHBG, BMP2, BMP4 | HDAC4 1295/4885HDAC2 4031/4885HDAC8 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.