Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610895 | 1.00 | MAPT (0.42) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10613245 | 0.93 | ABCG2 (0.42) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9820503 | 0.93 | ABCG2 (0.42) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10611733 | 0.92 | NPC1 (0.52) | MAPTKMT2ALMNANPC1NFKB1 | |
| SCHEMBL10623765 | 0.92 | NPC1 (0.52) | MAPTKMT2ALMNANPC1NFKB1 | |
| SCHEMBL9820579 | 0.92 | NPC1 (0.52) | MAPTKMT2ALMNANPC1NFKB1 | |
| SCHEMBL10614070 | 0.92 | NPC1 (0.52) | MAPTKMT2ALMNANPC1NFKB1 | |
| SCHEMBL9156662 | 0.83 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL6865273 | 0.83 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL7799666 | 0.83 | ALDH1A1 (0.53) | KMT2AALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240184-B1 | ALPHA-METHYLCINNAMIC ACID ESTER DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4751018-A | DISCOLORATION INHIBITION | MITSUBISHI RAYON COMPANY LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0240184-A2 | Alpha-Methylcinnamic acid ester derivative and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |