Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.31 |
| ▸ | PRKCG | P05129 | 2/20 | 0.31 |
| ▸ | PRKCB | P05771 | 2/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCH | P24723 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 2/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556954 | 0.98 | EPHX1 (0.57) | EPHX1ALDH1A1CYP1A2TDP1SPHK1 | |
| SCHEMBL9820594 | 0.92 | EPHX1 (0.48) | EPHX1ALDH1A1CYP1A2 | |
| SCHEMBL540949 | 0.84 | — | — | |
| SCHEMBL7509604 | 0.81 | SIGMAR1 (0.40) | EPHX1ALDH1A1 | |
| SCHEMBL9432642 | 0.77 | EPHX1 (0.35) | EPHX1ALDH1A1 | |
| SCHEMBL3897217 | 0.77 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL25304106 | 0.76 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1SPHK1 | |
| SCHEMBL11122975 | 0.76 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1SPHK1 | |
| SCHEMBL25303980 | 0.76 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1SPHK1 | |
| SCHEMBL2731115 | 0.76 | EPHX1 (1.00) | EPHX1ALDH1A1CYP1A2TDP1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |