Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820785 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820751 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820709 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820661 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820847 | 0.99 | MEN1 (0.45) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9821007 | 0.95 | HCRTR2 (0.44) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL10553316 | 0.93 | HCRTR2 (0.51) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820787 | 0.90 | HCRTR2 (0.46) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820710 | 0.88 | HCRTR2 (0.49) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 | |
| SCHEMBL9820831 | 0.87 | HCRTR1 (0.47) | MEN1KMT2AALDH1A1HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296978-B1 | 1-BENZYL 2-OXO 5-ALKOXY PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINES | ROUSSEL-UCLAF (FR) | 1991-09-11 | — | — | EP | disclosed |