Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820618 | 0.88 | MEN1 (0.44) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL9820751 | 0.88 | MEN1 (0.44) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL9820661 | 0.88 | MEN1 (0.44) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL9820709 | 0.88 | MEN1 (0.44) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL9820785 | 0.88 | MEN1 (0.44) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL10554923 | 0.87 | HCRTR2 (0.47) | HCRTR2HCRTR1KMT2AALDH1A1S1PR5 | |
| SCHEMBL9820831 | 0.87 | HCRTR1 (0.47) | HCRTR2HCRTR1KMT2AMEN1HTT | |
| SCHEMBL9820847 | 0.86 | MEN1 (0.45) | HCRTR2HCRTR1KMT2AMEN1POLB | |
| SCHEMBL10649332 | 0.86 | KMT2A (0.42) | HCRTR2HCRTR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10553316 | 0.86 | HCRTR2 (0.51) | HCRTR2HCRTR1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296978-B1 | 1-BENZYL 2-OXO 5-ALKOXY PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINES | ROUSSEL-UCLAF (FR) | 1991-09-11 | — | — | EP | disclosed |