Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820890 | 0.76 | ALDH1A1 (0.31) | MAPTKMT2A | |
| SCHEMBL9820596 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9820708 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9820724 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9820856 | 0.71 | CYP1A2 (0.36) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9820595 | 0.70 | POLB (0.31) | — | |
| SCHEMBL9820734 | 0.70 | CYP1A2 (0.34) | — | |
| SCHEMBL11705589 | 0.69 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2AJAK2 | |
| SCHEMBL9820704 | 0.68 | CYP1A2 (0.33) | — | |
| SCHEMBL11310170 | 0.68 | KDM4E (0.36) | KDM4EMEN1MAPTKMT2ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |