SCHEMBL9820666

SCHEMBL9820666

Oc1c(Br)cc(Br)cc1Br.Oc1cccc(C(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
HTT P42858 2/20 0.55
OPRK1 P41145 1/20 0.55
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP3A4 P08684 1/20 0.48
MAPT P10636 5/20 0.45
LMNA P02545 3/20 0.45
CES2 O00748 1/20 0.41
MGLL Q99685 1/20 0.41
CFTR P13569 1/20 0.40
MAPK1 P28482 1/20 0.40
GAA P10253 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
XBP1 P17861 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
GABRA1 P14867 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40389 0.83 TSHR (0.54) MEN1KMT2ATSHRTDP1CYP3A4
SCHEMBL29438909 0.83 TSHR (0.54) MEN1KMT2ATSHRTDP1CYP3A4
Hydrochloric Acid SCHEMBL30129608 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
SCHEMBL29661200 0.81 CES2 (0.57) MEN1KMT2ATSHRTDP1CYP3A4
SCHEMBL27511811 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
SCHEMBL28779162 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
Hydrochloric Acid SCHEMBL30994527 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
Water SCHEMBL27470131 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
SCHEMBL8724379 0.81 TSHR (0.52) MEN1KMT2ATSHRTDP1CYP3A4
Formaldehyde SCHEMBL7528010 0.77 CES2 (0.53) MEN1KMT2AHTTTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230382-B1 ADDITIVE FOR LUBRICATING OILS AND HYDROCARBON FUELS CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1991-11-06 EP disclosed
US-4710201-A FUEL ADDITIVES CHEVRON RESEARCH COMPANY (US) 1987-12-01 US disclosed
US-4695391-A Modified succinimides (IX) CHEVRON RESEARCH COMPANY (US) 1987-09-22 US disclosed
EP-0230382-A2 Additive for lubricating oils and hydrocarbon fuels CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1987-07-29 EP disclosed