Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 4/20 | 0.42 |
| ▸ | GBA1 | P04062 | 4/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684888 | 0.95 | GLB1 (0.44) | GLB1GBA1SPHK1GUSBS1PR1 | |
| SCHEMBL5366837 | 0.89 | GLB1 (0.50) | GLB1GBA1SPHK1GUSBS1PR1 | |
| SCHEMBL293950 | 0.84 | GBA1 (0.41) | GLB1GBA1SPHK1GUSBS1PR1 | |
| SCHEMBL294460 | 0.84 | GBA1 (0.41) | GLB1GBA1SPHK1GUSBS1PR1 | |
| SCHEMBL294624 | 0.80 | GLB1 (0.44) | GLB1GBA1SPHK1GUSBS1PR1 | |
| SCHEMBL23473144 | 0.78 | GLB1 (0.55) | GLB1GBA1SPHK1GUSB | |
| Ammonia Solution, Strong SCHEMBL9805948 | 0.77 | GLB1 (0.53) | GLB1GBA1 | |
| SCHEMBL4682864 | 0.75 | — | — | |
| SCHEMBL510722 | 0.74 | S1PR2 (0.42) | GBA1SPHK1GUSBS1PR1S1PR3 | |
| SCHEMBL293106 | 0.74 | S1PR2 (0.42) | GBA1SPHK1GUSBS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |