⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14232939 | 0.78 | CYP1A2 (0.41) | — | |
| SCHEMBL5962272 | 0.76 | ARG1 (0.30) | — | |
| SCHEMBL5962257 | 0.76 | ARG1 (0.30) | — | |
| SCHEMBL9820849 | 0.75 | GLB1 (0.42) | — | |
| SCHEMBL27770558 | 0.73 | — | — | |
| SCHEMBL15787948 | 0.73 | — | — | |
| SCHEMBL19088450 | 0.71 | — | — | |
| SCHEMBL4684888 | 0.69 | GLB1 (0.44) | — | |
| SCHEMBL10290823 | 0.68 | — | — | |
| SCHEMBL9562924 | 0.67 | SIGMAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| CN-1306935-C | Vasopressin antagonist and oxytocin antagonist | OTASUKA PHARMACEUTICAL CO LTD (JP) | 2007-03-28 | — | — | CN | disclosed |
| CN-1039999-C | Vasopressin antagonist and oxytocin antagonist, process for their preparation and pharmaceutical compositions containing them | OTSUKA CHEMICAL CO LTD (JP) | 1998-09-30 | — | — | CN | disclosed |
| CN-1183277-A | Vasopressin antagonist and oxytocin antagonist | OTASUKA PHARMACEUTICAL CO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| CN-1098716-A | Vasopressin antagonists and oxytocin antagonists | OTSUKA CHEMICAL CO LTD (JP) | 1995-02-15 | — | — | CN | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |