Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288267 | 0.86 | FFAR1 (0.55) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL301271 | 0.86 | FFAR1 (0.55) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL1474207 | 0.86 | FFAR1 (0.55) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL12999402 | 0.84 | HTT (0.51) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL1829983 | 0.80 | ALDH1A1 (0.69) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL16232159 | 0.79 | ALDH1A1 (0.64) | HTTLMNAMAPTTDP1CYP1A2 | |
| SCHEMBL2778214 | 0.78 | FFAR1 (0.48) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL2778217 | 0.78 | FFAR1 (0.48) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL1833981 | 0.78 | SLC6A2 (0.50) | TRPV1SLC6A2HTTNPC1LMNA | |
| SCHEMBL10692822 | 0.77 | SLC6A2 (0.56) | TRPV1SLC6A2HTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |