Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 11/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27091869 | 0.84 | HCRTR2 (0.53) | HCRTR2HCRTR1MEN1KMT2ATP53 | |
| SCHEMBL9820787 | 0.79 | HCRTR2 (0.46) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL24434648 | 0.78 | TP53 (0.50) | HCRTR2HCRTR1TP53MDM2EHMT2 | |
| SCHEMBL9821007 | 0.77 | HCRTR2 (0.44) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL288652 | 0.76 | P2RX7 (0.56) | HCRTR2HCRTR1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL289574 | 0.76 | P2RX7 (0.56) | HCRTR2HCRTR1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL288651 | 0.76 | P2RX7 (0.56) | HCRTR2HCRTR1ALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9820847 | 0.76 | MEN1 (0.45) | HCRTR2HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7407552 | 0.75 | HCRTR2 (0.50) | HCRTR2HCRTR1MEN1KMT2ATP53 | |
| SCHEMBL2265479 | 0.75 | HCRTR2 (0.50) | HCRTR2HCRTR1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296978-B1 | 1-BENZYL 2-OXO 5-ALKOXY PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINES | ROUSSEL-UCLAF (FR) | 1991-09-11 | — | — | EP | disclosed |
| US-4882350-A | TREATMENT OF INTELLECTUAL OR NERVOUS ASTHENIAS, MEMORY FAILURES | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0296978-A2 | 1-Benzyl 2-oxo 5-alkoxy pyrrolidine derivatives, process for their preparation, compositions containing them and their use in medicines | ROUSSEL-UCLAF (FR) | 1988-12-28 | — | — | EP | disclosed |