Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820989 | 0.82 | ADRB2 (0.40) | ADRB2ADRB1ADRB3ADRA1AADRA2A | |
| SCHEMBL11639709 | 0.80 | ADRB2 (0.54) | ADRB2ADRB1ADRB3ADRA1ACYP2D6 | |
| SCHEMBL9820997 | 0.75 | ADRB2 (0.67) | ADRB2ADRB1ADRB3ADRA1AADRA2A | |
| SCHEMBL1645001 | 0.71 | HDAC1 (0.53) | HDAC1HDAC6LMNA | |
| SCHEMBL9821076 | 0.70 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA1AADRA2A | |
| Hydrochloric Acid SCHEMBL11641795 | 0.69 | ADRB2 (0.53) | ADRB2ADRB1ADRB3ADRA1ATSHR | |
| SCHEMBL10485699 | 0.66 | ADRB2 (0.65) | ADRB2ADRB1ADRB3CYP2D6TSHR | |
| SCHEMBL21685346 | 0.66 | TSHR (0.48) | TSHRMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL31257778 | 0.66 | HDAC1 (0.45) | TSHRHDAC1HDAC6 | |
| SCHEMBL13061726 | 0.66 | CA1 (0.41) | ADRB2ADRB1ADRB3TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224001-B1 | ANTHRANILONITRILE DERIVATIVES AND RELATED COMPOUNDS AS USEFUL AGENTS FOR PROMOTING GROWTH, IMPROVING FEED EFFICIENCY, AND FOR INCREASING THE LEAN MEAT TO FAT RATIO OF WARM-BLOODED ANIMALS | AMERICAN CYANAMID COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4863959-A | Anthranilonitrile derivatives as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0224001-A1 | Anthranilonitrile derivatives and related compounds as useful agents for promoting growth, improving feed efficiency, and for increasing the lean meat to fat ratio of warm-blooded animals | AMERICAN CYANAMID COMPANY (US) | 1987-06-03 | — | — | EP | disclosed |