Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | GFER | P55789 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CTSV | O60911 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821210 | 0.86 | MAPT (0.67) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL10626357 | 0.81 | MAPT (0.71) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL6582107 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL9821023 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL4588988 | 0.79 | MAPT (0.58) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL9820922 | 0.78 | MAPT (0.64) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL9821177 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL5174834 | 0.77 | MAPT (0.75) | MAPTMEN1KMT2AGFERGAA | |
| SCHEMBL11195246 | 0.76 | F2 (0.61) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7829819 | 0.76 | MAPT (0.65) | MAPTMEN1KMT2AGFERGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220613-B1 | DIRECT HAIR DYEING COMPOSITION CONTAINING DERIVATIVES OF NITRODIPHENYL AMINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0220613-A1 | Direct hair dyeing composition containing derivatives of nitrodiphenyl amine | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-06 | — | — | EP | disclosed |