Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820922 | 0.86 | MAPT (0.64) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL9821210 | 0.83 | MAPT (0.67) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL10628250 | 0.82 | MAPT (0.54) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL9821177 | 0.81 | MAPT (0.56) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL9820982 | 0.80 | MAPT (0.66) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL9821173 | 0.80 | MAPT (0.58) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL9820943 | 0.74 | MAPT (0.51) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL10623575 | 0.74 | MAPT (0.56) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL10623676 | 0.73 | MAPT (0.62) | MAPTKMT2AMEN1GFERRECQL | |
| SCHEMBL2920267 | 0.73 | CTSV (0.69) | MAPTKMT2AMEN1GFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220613-B1 | DIRECT HAIR DYEING COMPOSITION CONTAINING DERIVATIVES OF NITRODIPHENYL AMINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0220613-A1 | Direct hair dyeing composition containing derivatives of nitrodiphenyl amine | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-06 | — | — | EP | disclosed |