Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821161 | 0.86 | ALDH1A1 (0.42) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19628622 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12466620 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4209116 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL799468 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL301501 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4203114 | 0.79 | FFAR1 (0.81) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2189688 | 0.78 | FFAR1 (0.35) | FFAR1FFAR4 | |
| SCHEMBL9820889 | 0.78 | MAPT (0.44) | FFAR1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2189684 | 0.78 | FFAR1 (0.35) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |