Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10880062 | 0.86 | NT5E (0.65) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL10881471 | 0.84 | NT5E (0.66) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL11104382 | 0.83 | NT5E (0.70) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL7839318 | 0.82 | MAPT (0.72) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL10347230 | 0.81 | NT5E (0.61) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL7838995 | 0.80 | MAPT (0.55) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL11110261 | 0.79 | NT5E (0.69) | MAPTMEN1KMT2ATDP1GFER | |
| SCHEMBL30165662 | 0.79 | ALDH1A1 (0.66) | MAPTMEN1KMT2ATDP1NT5E | |
| SCHEMBL709336 | 0.79 | ALDH1A1 (0.66) | MAPTMEN1KMT2ATDP1NT5E | |
| SCHEMBL7829819 | 0.78 | MAPT (0.65) | MAPTMEN1KMT2ATDP1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220613-B1 | DIRECT HAIR DYEING COMPOSITION CONTAINING DERIVATIVES OF NITRODIPHENYL AMINE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-05-08 | — | — | EP | disclosed |
| US-4756716-A | Cosmetic carrier, surfactant, nitrodiphenylamine hair dyes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0220613-A1 | Direct hair dyeing composition containing derivatives of nitrodiphenyl amine | Henkel Kommanditgesellschaft auf Aktien (DE) | 1987-05-06 | — | — | EP | disclosed |