Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754130 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL9564928 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL23172157 | 0.80 | ESR1 (0.41) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL22651899 | 0.79 | ESR1 (0.40) | ALDH1A1KDM4EMEN1NPC1THRB | |
| Hydrochloric Acid SCHEMBL5718674 | 0.79 | ESR1 (0.43) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL6550713 | 0.78 | ESR1 (0.44) | ALDH1A1ESR1SLC6A2SLC6A4HDAC6 | |
| SCHEMBL5500306 | 0.77 | ESR1 (0.46) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL7719647 | 0.77 | HDAC6 (0.49) | ALDH1A1KDM4EMEN1NPC1THRB | |
| SCHEMBL6299189 | 0.77 | TSHR (0.46) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL31718395 | 0.77 | TSHR (0.46) | ALDH1A1MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298803-B1 | PROCESS FOR THE PERHALOALKYLATION OF AROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1991-09-04 | — | — | EP | disclosed |
| EP-0206951-B1 | PROCESS FOR THE PERFLUOROALKYLATION OF AROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1990-03-21 | — | — | EP | disclosed |
| EP-0298803-A1 | Process for the perhaloalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1989-01-11 | — | — | EP | disclosed |
| US-4731450-A | Process for perfluoroalkylation of aromatic derivatives | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-03-15 | — | — | US | disclosed |
| EP-0206951-A2 | Process for the perfluoroalkylation of aromatic derivatives | RHONE-POULENC CHIMIE (FR) | 1986-12-30 | — | — | EP | disclosed |
| US-4392998-A | One pot diazotization, coupling and quaternization of aminotriazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| EP-0036505-B1 | PROCESS FOR THE PREPARATION OF CATIONIC DYESTUFFS AND THEIR USE IN DYEING ACID-MODIFIED SYNTHETIC FIBRES | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0036505-A2 | Process for the preparation of cationic dyestuffs and their use in dyeing acid-modified synthetic fibres | BAYER AG (DE) | 1981-09-30 | — | — | EP | disclosed |