Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.62 |
| ▸ | ARG2 | P78540 | 1/20 | 0.62 |
| ▸ | NOS2 | P35228 | 3/20 | 0.55 |
| ▸ | NOS1 | P29475 | 2/20 | 0.55 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | BHMT | Q93088 | 6/20 | 0.42 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296784 | 1.00 | ARG1 (0.62) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL110108 | 1.00 | ARG1 (0.62) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL17633808 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Bromide SCHEMBL5505432 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL5494298 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Bromide SCHEMBL5505430 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL9815370 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL8472319 | 0.98 | ARG1 (0.60) | ARG1ARG2NOS2NOS1NOS3 | |
| Cysteamine SCHEMBL11584063 | 0.92 | ARG1 (0.55) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL17361239 | 0.88 | ARG1 (0.69) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181578-B1 | ANTIBIOTIC POLYPEPTIDE, PROCESS FOR ITS PREPARATION AND ITS USE | Dr. Karl Thomae GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0181578-A2 | Antibiotic polypeptide, process for its preparation and its use | Dr. Karl Thomae GmbH (DE) | 1986-05-21 | — | — | EP | disclosed |