SCHEMBL9821340

SCHEMBL9821340

C=C(C)C(=O)OC(CC)[Si]1([Si](C)(C)C)CCCC([Si](C)(C)C)([Si](C)(C)C)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6907679 0.72
SCHEMBL8450805 0.70
SCHEMBL4059700 0.69
SCHEMBL11152841 0.68
SCHEMBL8935038 0.68
SCHEMBL6664707 0.67
SCHEMBL27861084 0.67 TSHR (0.33)
SCHEMBL2142345 0.66
SCHEMBL4340354 0.65
SCHEMBL6036462 0.64 TSHR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4818801-A IMPROVED OXYGEN PERMEABILITY; CONTACT LENSES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-04 US claimed
US-4440918-A OXYGEN PERMEABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-03 US claimed
EP-0211067-B1 OXYGEN-PERMEABLE LENSES Bausch &amp; Lomb Incorporated (US) 1991-03-13 EP disclosed
US-4818801-A IMPROVED OXYGEN PERMEABILITY; CONTACT LENSES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-04 US disclosed
US-4680149-A CONTACT LENS INTERNATIONAL HYDRON CORPORATION (US) 1987-07-14 US disclosed
EP-0084406-B1 OPHTHALMIC DEVICE COMPRISING A POLYMER OF A TELECHELIC PERFLUOROPOLYETHER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-07-16 EP disclosed
US-4440918-A OXYGEN PERMEABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-03 US disclosed
EP-0084406-A1 Ophthalmic device comprising a polymer of a telechelic perfluoropolyether MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed