Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363547 | 1.00 | CYP19A1 (0.34) | CYP19A1GPR119KMT2ACYP3A4CYP2C9 | |
| SCHEMBL9821568 | 0.76 | ESR1 (0.40) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Propane SCHEMBL9821512 | 0.72 | CYP19A1 (0.35) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9821506 | 0.70 | CYP19A1 (0.33) | CYP19A1KMT2AGAAPOLB | |
| SCHEMBL9431443 | 0.67 | ALDH1A1 (0.50) | CYP19A1GPR119KMT2ACYP3A4CYP2C9 | |
| SCHEMBL9869670 | 0.65 | KMT2A (0.41) | KMT2ALMNAALDH1A1 | |
| SCHEMBL9821405 | 0.65 | KMT2A (0.41) | KMT2ALMNAALDH1A1 | |
| SCHEMBL9821500 | 0.65 | POLB (0.35) | CYP19A1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL9821394 | 0.64 | MAPT (0.44) | CYP19A1KMT2ACYP3A4CYP1A2LMNA | |
| SCHEMBL9821498 | 0.64 | MAPT (0.44) | CYP19A1KMT2ACYP3A4CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349580-B1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| EP-0349580-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES. | DU PONT (US) | 1990-01-10 | — | — | EP | disclosed |
| WO-1988007040-A1 | FUNGICIDAL AMINOTRIAZOLES AND AMINOIMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-22 | — | — | WO | disclosed |
| EP-0283245-A1 | Fungicidal aminotriazoles and aminoimidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-21 | — | — | EP | disclosed |